Article

Randomization based evaluation of distinct topological and cancer expression characteristics of mutually acting gene pairs

2024-10-11

Abstract excerpt

Small scale molecular network patterns and motifs are crucial for systems level understanding of cellular information transduction. A subgroup of such patterns consists of only 2 molecules, which we named as mutually acting pairs. Using randomizations, we statistically explored such gene pair designs, i.e. mutually positive (PP) or negative (NN) and positive-negative (PN) pairs, in two comprehensive and distinct l...

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Literature Corpus work: e6ae8aac-3868-56d1-86d4-dba289798008
DOI: 10.1101/2024.10.09.617344

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