Article

Early Immune Pathology and Persistent Dysregulation Characterise Severe COVID-19

2020-12-29

Abstract excerpt

In a study of 207 SARS-CoV2-infected individuals with a range of severities followed over 12 weeks from symptom onset, we demonstrate that an early robust immune response, without systemic inflammation, is characteristic of asymptomatic or mild disease. Those presenting to hospital had delayed adaptive responses and systemic inflammation already evident at around symptom onset. Such early evidence of inflammation...

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Literature Corpus work: e67f0207-e059-51be-98ec-6d20b0e0adf5
DOI: 10.2139/ssrn.3757074

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