Article

Immunological and clinical markers of post-acute sequelae of COVID-19: Insights from mild and severe cases six months post-infection

2025-02-21

Abstract excerpt

<h4>SUMMARY</h4> Post-acute sequelae of COVID-19 (PASC) is a complex and multifaceted clinical challenge requiring to emphasize its underlying pathophysiological mechanisms. This study assessed hundreds of virological, serological, immunological, and tissue damage biomarkers in two patient cohorts who experienced mild (n=270) or severe (n=188) COVID-19, 6 to 9 months post-initial infection, and in which 40% and 5...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 923d3438-b225-52be-aa4e-6a551035d23c
DOI: 10.1101/2025.02.18.638851

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Immunological and clinical markers of post-acute sequelae of COVID-19: Insights from mild and severe cases six months post-infectionDOI 10.1101/2025.02.18.638851Read

Immunological and Clinical Markers of Post‐acute Sequelae of COVID‐19: Insights from Mild and Severe Cases 6 Months Post‐infectionSemantic proximity Read

Blood T cell phenotypes correlate with fatigue severity in post-acute sequelae of COVID-19.Semantic proximity Read

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistenceSemantic proximity Read

Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19Semantic proximity Read

Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA responseSemantic proximity Read

Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19Semantic proximity Read

Early immune responses have long-term associations with clinical, virologic, and immunologic outcomes in patients with COVID-19Semantic proximity Read

A Longitudinal SARS-CoV-2 Biorepository for COVID-19 Survivors with and without Post-Acute SequelaeSemantic proximity Read

COVID-19 Clinical Severity, T Cell-Mediated Immune Response, and Correlates of Inflammation: Not an Intuitive GuessSemantic proximity Read

Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelaeSemantic proximity Read

Immune-Based Prediction of COVID-19 Severity and Chronicity Decoded Using Machine LearningSemantic proximity Read

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelaeSemantic proximity Read