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Article

A distinct innate immune signature marks progression from mild to severe COVID-19

25 Dec 2020

Abstract excerpt

Coronavirus disease 2019 (COVID-19) manifests with a range of severities, but immune signatures of mild and severe disease are still not fully understood. Here, we use mass cytometry and targeted proteomics to profile the innate immune response of patients with mild or severe COVID-19 and of healthy individuals. Sampling at different stages allows us to reconstruct a pseudo-temporal trajectory of the innate...

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PMID: 33521697
DOI: 10.1016/j.xcrm.2020.100166

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