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Identification of the 216kbp gene cluster and structure elucidation of gargantulides B and C, new complex 52-membered macrolides from <i>Amycolatopsis</i> sp

2021-08-11

Abstract excerpt

Gargantulides B and C, two new and highly complex 52-membered glycosylated macrolactones, were isolated from Amycolatopsis sp. strain CA-230715 during an antibacterial screening campaign. The structures of these giant macrolides were elucidated by 2D NMR spectroscopy and shown to be related to gargantulide A, although containing additional β -glucopyranose and/or α -arabinofuranose monosaccharides separately at...

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Literature Corpus work
e671084a-93f7-5176-a961-753d1b43ea2c
DOI
10.1101/2021.08.11.455926
Open publication

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Identification of the 216kbp gene cluster and structure elucidation of gargantulides B and C, new complex 52-membered macrolides from <i>Amycolatopsis</i> spDOI 10.1101/2021.08.11.455926
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