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Gut microbiome derived folate metabolite suppresses colorectal cancer progression

2026-07-15

Abstract excerpt

The gut microbiota influences colorectal cancer (CRC) progression, primarily through the secretion of small molecule metabolites. While numerous microbial products are known to drive CRC, endogenous protective mechanisms remain largely uncharacterized. Utilizing a folate metabolomics platform, we demonstrate that the healthy gut microbiota produces folinic acid (FA), a known chemotherapeutic adjuvant also known as...

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Literature Corpus work
e5eb51b4-d30d-5e93-bf46-656c896eb84f
DOI
10.64898/2026.07.14.738490
Open publication

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Gut microbiome derived folate metabolite suppresses colorectal cancer progressionDOI 10.64898/2026.07.14.738490
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