Article

Characterization of Structural Variation in Tibetans Reveals New Evidence of High-altitude Adaptation and Introgression

2020-12-02

Abstract excerpt

Structural variation (SV) acts as an essential mutational force shaping the evolution and function of the human genome. To investigate the role of SVs in high-altitude adaptation (HAA), we here generated a comprehensive catalog of SVs in a Chinese Tibetan (n = 15) and Han (n = 10) population using the nanopore sequencing technology. Among a total of 38,216 unique SVs in the catalog, 27% were sequence-resolved for...

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Literature Corpus work: e5ea357a-759f-5429-b0e1-4a5be7ec0b99
DOI: 10.1101/2020.12.01.401174

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