Article

Challenges in Humoral Immune Response to Adeno-Associated Viruses Determination

2024-12-10

Abstract excerpt

Adeno-associated viruses (AAVs) are non-pathogenic, replication-deficient viruses that have gained widespread attention for their application as gene therapy vectors. While these vectors offer high transduction efficiency and long-term gene expression, the host immune response poses a significant challenge to their clinical success. This review focuses on the obstacles of evaluating humoral response to AAVs. We di...

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Literature Corpus work: e5ceaaa7-3988-561c-886f-a7e0cb5e67f1
DOI: 10.20944/preprints202412.0766.v1

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