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MARS: Improved De Novo Peptide Candidate Selection for Non-Canonical Antigen Target Discovery in Cancer

2022-08-03

Abstract excerpt

<title>Abstract</title> <p>Cryptic Human Leukocyte Antigen (HLA)-presented peptide identification from unannotated genome sources is a priority for target antigen discovery for development of next generation immunotherapies in cancer. Current immunopeptidomic approaches utilize the integration of transcriptomics data to inform spectral interpretation, however, recent observations that tumour-associated antigen-en...

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Literature Corpus work: e5c5fd30-286a-5997-bb1f-4f95d76708cb
DOI: 10.21203/rs.3.rs-1890352/v1

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