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Exploring Moringa oleifera Phytochemicals as Potential Inhibitors for HIF- 1α/VEGF/GLUT1 pathway in Breast Cancer Using Molecular Docking, MD Simulations, and DFT Analysis

2025-05-14

Abstract excerpt

<title>Abstract</title> <p> Breast cancer is among the most heterogeneous and aggressive diseases and a foremost cause of death in women globally. Hypoxic activation of HIF-1α in breast cancers triggers the transcription of a battery of genes encoding proteins that facilitate tumor growth and metastasis and is correlated with a poor prognosis. Based on the reported cytotoxic and anti-cancer properties of <itali...

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Literature Corpus work: e5bc2d3b-2f52-5577-ab8f-c0d2a732a7f5
DOI: 10.21203/rs.3.rs-6394662/v1

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