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Molecular Targets and Mechanisms of Piperine Against Breast Cancer: A Network Pharmacology, Molecular Docking Analysis, and Toxicity Prediction

27 May 2025

Abstract excerpt

Breast cancer is still one of the major causes of cancer-related death worldwide, which highlights the need for cutting-edge therapeutic strategies. An alkaloid called piperine, which comes from Piper longum, has demonstrated encouraging anticancer effects. Piperine modulates different cancer signaling pathways and enzymes such as P53, apoptosis, and cell cycle regulation. Protein function and signaling pathway...

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PMID: 40424641
DOI: 10.1002/cbdv.202403180

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