Article

Serum levels of specialised pro-resolving molecule pathways are greatly increased in SARS-CoV-2 patients and correlate with markers of the adaptive immune response

2021-12-11

Abstract excerpt

<h4>Background</h4> Specialised pro-resolution molecules (SPMs) halt the transition to chronic pathogenic inflammation. We aimed to quantify serum levels of pro- and anti-inflammatory bioactive lipids in SARS-CoV-2 patients, and to identify potential relationships with innate responses and clinical outcome. <h4>Methods</h4> Serum from 50 hospital admitted inpatients (22 female, 28 male) with confirmed symptomatic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e5b69854-5809-5e1a-bc11-a502f534d57a
DOI: 10.1101/2021.12.07.21267409

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Serum levels of specialised pro-resolving molecule pathways are greatly increased in SARS-CoV-2 patients and correlate with markers of the adaptive immune responseDOI 10.1101/2021.12.07.21267409Read

Multi-omics provide evidence for an anti-inflammatory immune signature and metabolic alterations in patients with Long COVID Syndrome – an exploratory studySemantic proximity Read

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve InflammationSemantic proximity Read

Immunological and Biochemical Biomarker Alterations Among SARS-COV-2 Patients with Varying Disease Phenotypes in UgandaSemantic proximity Read

Immunological and biochemical biomarker alterations among SARS-COV-2 patients with varying disease phenotypes in Uganda.Semantic proximity Read

SARS-CoV2- infection as a trigger of humoral response against apolipoprotein A-1Semantic proximity Read

A patient-centric characterization of systemic recovery from SARS-CoV-2 infectionSemantic proximity Read

Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition moleculesSemantic proximity Read

Multi-Omics Provide Evidence for an Anti-Inflammatory Immune Signature and Metabolic Alterations in Patients with Long COVID Syndrome – an Exploratory StudySemantic proximity Read

Plasma Sphingomyelin Disturbances: Unveiling Its Dual Role as a Crucial Imunopathological Factor and a Severity Prognostic Biomarker in COVID-19Semantic proximity Read

The Coronavirus Envelope Is Modulated by Host Inflammation and Enriched in Bioactive Lipids Required for ReplicationSemantic proximity Read

Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infectionSemantic proximity Read

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoproteinSemantic proximity Read