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The in Vitro and in Vivo Antitumor Effect Associating With the Hippo-yap Signaling Pathway of Gallic Acid and Its Combination With Icotinib Hydrochloride on the Non-small Cell Lung Cancer Cellular and Xenograft Tumor-bearing Nude Mouse Models

2021-06-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been widely used as first-line therapy for patients with EGFR mutant non-small cell lung cancer (NSCLC). However, EGFR-TKIs treatment of NSCLC will inevitably produce acquired drug resistance. It greatly limits the therapeutic effect of TKI. Recent studies have found that some natural d...

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Literature Corpus work
e58f19f6-aa2a-5fd0-84c2-bec7fbebec5c
DOI
10.21203/rs.3.rs-618568/v1
Open publication

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The in Vitro and in Vivo Antitumor Effect Associating With the Hippo-yap Signaling Pathway of Gallic Acid and Its Combination With Icotinib Hydrochloride on the Non-small Cell Lung Cancer Cellular and Xenograft Tumor-bearing Nude Mouse ModelsDOI 10.21203/rs.3.rs-618568/v1
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