Article
Peruvoside is a new Src inhibitor that suppresses NSCLC cell growth and motility by downregulating multiple Src-EGFR-related pathways
2020-12-22
Abstract excerpt
<h4>Background: </h4> The tyrosine kinase Src plays an essential role in the progression of many cancers and is involved in several signalling pathways regulated by EGFR. To improve the efficacy of lung cancer treatments, this study aimed to identify novel compounds that can disrupt the Src-EGFR interaction to inhibit lung cancer progression and are less dependent on the EGFR mutation status than other compounds....
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Identifiers and source
- Literature Corpus work
- 368ec59f-9a6a-5e99-b417-59c6cd09b9b1
- DOI
- 10.21203/rs.3.rs-131947/v1
