Article

<i>ACTN3</i> genotype influences androgen response in skeletal muscle

2024-04-28

Abstract excerpt

<h4> Abstract </h4> Androgens are vital for the maintenance of muscle mass and their anabolic effects are primarily exerted through the androgen receptor (AR). Accumulating evidence in humans and mice suggests that circulating androgens, AR and androgen response are influenced by ACTN3 ( α- actinin-3), also known as “the gene for speed”. One in 5 people worldwide are α-actinin-3 deficient due to homozygous inhe...

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Literature Corpus work: e58b592d-38c8-5eda-814b-3104cf4805df
DOI: 10.1101/2024.04.25.591034

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