Article

<i>ACTN3</i> genotype influences skeletal muscle mass regulation and response to dexamethasone

2020-11-23

Abstract excerpt

Homozygosity for the common ACTN3 null polymorphism ( ACTN3 577X) results in α-actinin-3 deficiency in ~20% of humans worldwide and is linked to reduced sprint and power performance in both elite athletes and the general population. α-Actinin-3 deficiency is also associated with reduced muscle mass and strength, increased risk of sarcopenia in the elderly, and altered response to muscle wasting induced by denerv...

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Literature Corpus work: 7a64a685-3147-5063-9eb3-73cbf5db0bd0
DOI: 10.1101/2020.11.20.392282

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