Article

Reproducible generation of Nipah virus pseudovirions with uniform expression of F and G surface glycoproteins for high-throughput neutralization assays

2025-04-07

Abstract excerpt

Nipah virus (NiV) is a pathogen to be handled in BSL-4 facilities. Multiple surrogate systems such as virus-like particles (VLPs) and pseudoviruses enable carrying out NiV neutralization assays and study of virus entry pathways in biosafety level-2 (BSL-2) facilities. These are dual protein expression and surface display systems comprising NiV structural glycoproteins F and G as the key components. During generati...

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Literature Corpus work: e4dadff5-268a-5ea7-b96b-e91495bfef3d
DOI: 10.1101/2025.04.07.647518

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