Article
Novel transcription and replication-competent virus-like particles system modelling the Nipah virus life cycle
12 Jun 2024
Abstract excerpt
Nipah virus (NiV), a highly pathogenic Henipavirus in humans, has been responsible for annual outbreaks in recent years. Experiments involving live NiV are highly restricted to biosafety level 4 (BSL-4) laboratories, which impedes NiV research. In this study, we developed transcription and replication-competent NiV-like particles (trVLP-NiV) lacking N, P, and L genes. This trVLP-NiV exhibited the ability to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
