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Article

Methylome and transcriptome profiling in Myasthenia Gravis monozygotic twins.

Journal of autoimmunity - 1 Aug 2017

Mamrut Shimrat, Avidan Nili, Truffault Frédérique, Staun-Ram Elsebeth, Sharshar Tarek, Eymard Bruno, Frenkian Mélinée, Pitha Jiri, de Baets Marc, Servais Laurent, Berrih-Aknin Sonia, Miller Ariel

Abstract excerpt

OBJECTIVE: To identify novel genetic and epigenetic factors associated with Myasthenia gravis (MG) using an identical twins experimental study design. METHODS: The transcriptome and methylome of peripheral monocytes were compared between monozygotic (MZ) twins discordant and concordant for MG, as well as with MG singletons and healthy controls, all females. Sets of differentially expressed genes and...

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PMID: 28549776
DOI: 10.1016/j.jaut.2017.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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