Article

Folate ameliorates arrhythmia in patient-derived TANGO2-deficient iPSC-cardiomyocytes

2022-06-22

Abstract excerpt

<title>Abstract</title> <p>TANGO2-deficient disorder (TDD) is an autosomal recessive genetic disease caused by biallelic loss-of-function variants in <italic>TANGO2</italic> gene. TDD-associated cardiac arrythmias are typically recalcitrant to standard antiarrhythmic medications and constitute the leading cause of death. Here, we established novel patient-derived induced pluripotent stem cell differentiated cardi...

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Literature Corpus work: e4d50beb-fea7-5b63-a055-8c91afd2ab58
DOI: 10.21203/rs.3.rs-1778084/v1

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