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In vivo complex haploinsufficiency-based genetic analysis identifies a transcription factor circuit regulating <i>Candida albicans</i> oropharyngeal infection and epithelial cell endocytosis

2021-05-24

Abstract excerpt

Oropharyngeal candidiasis (OPC) is a common infection that complicates a wide range of medical conditions which can cause either mild or severe disease depending on the patient. The pathobiology of OPC shares many features with candidal biofilms of abiotic surfaces. The transcriptional regulation of C. albicans formation of biofilms on abiotic surfaces has been extensively characterized and involves six key trans...

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Literature Corpus work
e4c21586-8d72-53b9-aef3-8235c5de2ef2
DOI
10.1101/2021.05.24.445409
Open publication

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In vivo complex haploinsufficiency-based genetic analysis identifies a transcription factor circuit regulating <i>Candida albicans</i> oropharyngeal infection and epithelial cell endocytosisDOI 10.1101/2021.05.24.445409
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