Article

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

2019-07-11

Abstract excerpt

Although the process of autophagy has been extensively studied, the mechanisms that regulate it remain insufficiently understood. The ability to manipulate autophagy is important not only for addressing fundamental biological questions, but also for its possible application to the treatment of various human diseases. To identify novel regulators of autophagy, we performed a whole-genome CRISPR/Cas9 knockout screen...

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Literature Corpus work: e49a1955-6878-5cb6-bbb5-0b2b835fa74a
DOI: 10.1101/699124

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