Article

Triangulating molecular evidence to prioritise candidate causal genes at established atopic dermatitis loci

2020-11-30

Abstract excerpt

<h4>Background</h4> Genome-wide association studies for atopic dermatitis (AD, eczema) have identified 25 reproducible loci associated in populations of European descent. We attempt to prioritise candidate causal genes at these loci using a multifaceted bioinformatic approach and extensive molecular resources compiled into a novel pipeline: ADGAPP (Atopic Dermatitis GWAS Annotation & Prioritisation Pipeline). <h4>...

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Literature Corpus work: e4923e95-2367-5766-bb86-dbd4d56ad762
DOI: 10.1101/2020.11.30.20240838

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