Article
What Have We Learned from GWAS for Atopic Dermatitis?
The Journal of investigative dermatology - 1 Jan 2021
Brown Sara J
Abstract excerpt
GWASs have revealed multiple loci associated with atopic dermatitis (AD). Some have confirmed pre-existing knowledge, including the role of skin barrier and type 2 inflammation in AD pathogenesis, whereas others have provided newer insights, including evidence of autoimmunity and previously unrecognized genes controlling epidermal differentiation. The majority of risk loci are in intergenic regions for which...
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