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Article

Triangulating Molecular Evidence to Prioritize Candidate Causal Genes at Established Atopic Dermatitis Loci

23 Apr 2021

Abstract excerpt

GWASs for atopic dermatitis have identified 25 reproducible loci. We attempt to prioritize the candidate causal genes at these loci using extensive molecular resources compiled into a bioinformatics pipeline. We identified a list of 103 molecular resources for atopic dermatitis etiology, including expression, protein, and DNA methylation quantitative trait loci datasets in the skin or immune-relevant tissues,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33901562
DOI: 10.1016/j.jid.2021.03.027

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