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Effect of<i>MAOA</i>DNA methylation on human<i>in vivo</i>protein expression measured by [<sup>11</sup>C]harmine PET in healthy and depressed individuals

2022-04-02

Abstract excerpt

Epigenetic modifications, such as DNA methylation, are understood as an intermediary between environmental factors affecting disease risk and pathophysiologic changes to brain structure and function. Cerebral monoamine oxidase A (MAO-A) levels are altered in depression, as are DNA methylation levels within the MAOA gene, particularly in the promoter / exon I / intron I region. An effect of MAOA methylation on peri...

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Literature Corpus work
e48b9c33-9338-5bbb-b1a3-7a09005d3794
DOI
10.1101/2022.03.29.22273110
Open publication

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Effect of<i>MAOA</i>DNA methylation on human<i>in vivo</i>protein expression measured by [<sup>11</sup>C]harmine PET in healthy and depressed individualsDOI 10.1101/2022.03.29.22273110
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