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Article

Cortico-limbic connectivity in MAOA-L carriers is vulnerable to acute tryptophan depletion.

Human brain mapping - 1 Mar 2017

Eisner Patrick, Klasen Martin, Wolf Dhana, Zerres Klaus, Eggermann Thomas, Eisert Albrecht, Zvyagintsev Mikhail, Sarkheil Pegah, Mathiak Krystyna A, Zepf Florian, Mathiak Klaus

Abstract excerpt

INTRODUCTION: A gene-environment interaction between expression genotypes of the monoamine oxidase A (MAOA) and adverse childhood experience increases the risk of antisocial behavior. However, the neural underpinnings of this interaction remain uninvestigated. A cortico-limbic circuit involving the prefrontal cortex (PFC) and the amygdala is central to the suppression of aggressive impulses and is modulated by...

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Identifiers

PMID: 27935229
DOI: 10.1002/hbm.23475
PMCID: PMC6866997

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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