Article

Impact of Measurement Imprecision on Genetic Association Studies of Cardiac Function

2023-02-18

Abstract excerpt

<h4>Background</h4> Recent studies have leveraged quantitative traits from imaging to amplify the power of genome-wide association studies (GWAS) to gain further insights into the biology of diseases and traits. However, measurement imprecision is intrinsic to phenotyping and can impact downstream genetic analyses. <h4>Methods</h4> Left ventricular ejection fraction (LVEF), an important but imprecise quantitative...

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Literature Corpus work: e4271f0e-dc77-5bce-be79-b45883d871bf
DOI: 10.1101/2023.02.16.23286058

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