Article
Impact of Measurement Noise on Genetic Association Studies of Cardiac Function.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2024
Vukadinovic Milos, Renjith Gauri, Yuan Victoria, Kwan Alan, Cheng Susan C, Li Debiao, Clarke Shoa L, Ouyang David
Abstract excerpt
Recent research has effectively used quantitative traits from imaging to boost the capabilities of genome-wide association studies (GWAS), providing further understanding of disease biology and various traits. However, it's important to note that phenotyping inherently carries measurement error and noise that could influence subsequent genetic analyses. The study focused on left ventricular ejection fraction...
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