Article

Estimating the prevalence of potential and actionable drug-gene interactions in Irish primary care: a cross-sectional study

2024-04-16

Abstract excerpt

<h4>Aims: </h4>: Pharmacogenetics (PGx) is increasingly recognised as a strategy for medicines optimisation and prevention of adverse drug reactions. According to guidelines produced by the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Dutch Pharmacogenetic Working Group (DPWG), most medicines with drug-gene interactions (DGIs) are prescribed in primary care. This study aimed to estimate the p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e40b4fb1-b67a-556e-96f0-c2b3e7f068c0
DOI: 10.22541/au.171328607.78649954/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Estimating the prevalence of potential and actionable drug-gene interactions in Irish primary care: a cross-sectional studyDOI 10.22541/au.171328607.78649954/v1Read

Estimating the potential impact of implementing pre-emptive pharmacogenetic testing in primary care across the UK.Semantic proximity Read

Estimated nationwide impact of implementing a preemptive pharmacogenetic panel approach to guide drug prescribing in primary care in The NetherlandsSemantic proximity Read

Use of Pharmacogenetic Drugs by the Dutch PopulationSemantic proximity Read

Evaluating genotype-treatment interactions for high-risk medications in British general practice: a retrospective cohort study using UK Biobank.Semantic proximity Read

Genotype-predicted drug response phenotypes and their co-occurrence with dispensed medicines among 738,531 participants in the UK Our Future Health studySemantic proximity Read

Prevalence of actionable pharmacogenetic variants and high‐risk drug prescriptions: A Swiss hospital‐based cohort studySemantic proximity Read

A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.Semantic proximity Read

Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems.Semantic proximity Read

The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responsesSemantic proximity Read

Pharmacogenetics at Scale: An Analysis of the UK Biobank.Semantic proximity Read

Pharmacotherapy Associated with CYP2C19, CYP2C9, CYP2D6, and UGT1A1 Genes in Population Sample: Observational Cross Sectional Analytical StudySemantic proximity Read

Predicting drug-drug and drug-gene interactions in a community pharmacy population.Semantic proximity Read