Pharmacogenomic-Guided Prescribing for Treatment-Resistant Mental Health Conditions in Australian Primary Care: A Single-GP Practice Retrospective Observation of 29 Patients.

doi:10.3390/ijms27167329

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Article

Pharmacogenomic-Guided Prescribing for Treatment-Resistant Mental Health Conditions in Australian Primary Care: A Single-GP Practice Retrospective Observation of 29 Patients.

International journal of molecular sciences - 17 Aug 2026

Beer Cristina, Rae Fiona, Watt Mikayla, Semmler Annalese, Voisey Joanne

Abstract excerpt

Treatment-resistant mental health conditions are common in primary care and challenging for clinicians. Trial-and-error prescribing can prolong morbidity and increase adverse drug reactions (ADRs). Pharmacogenomic (PGx) testing enables individualised prescribing by identifying gene-drug interactions affecting psychotropic response. Thirty adults with treatment-resistant mental health conditions underwent PGx...

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Australia
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6
Mental Disorders
Pharmacogenomic Testing
Precision Medicine

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Primary Health Care

Psychotropic Drugs

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PMID: 42653333
DOI: 10.3390/ijms27167329
PMCID: PMC13513532

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CYP2C19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.