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Heteroresistance to cefiderocol in carbapenem-resistant Acinetobacter baumannii in the CREDIBLE-CR study was not linked to clinical outcomes: a post hoc analysis

15 Nov 2023

Abstract excerpt

ABSTRACT This study aimed to determine the proportion of heteroresistance in carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex (CRAB) isolates in the cefiderocol arm of the randomized, Phase 3 CREDIBLE-CR study by population analysis profiling (PAP) and to determine whether there is any correlation between heteroresistance and clinical outcomes. PAP phenotypes [PAP-susceptible (PAP-S),...

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PMID: 37966262
DOI: 10.1128/spectrum.02371-23

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