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Transmission cluster of cefiderocol-non-susceptible carbapenem-resistant Acinetobacter baumannii in cefiderocol-naïve individuals

29 Nov 2024

Abstract excerpt

Abstract Background During prolonged FDC therapy, the emergence of FDC non-susceptibility in CRAB has been reported. Here, we report a transmission cluster of FDC-non-susceptible CRAB in four patients, all naïve to FDC treatment, characterized by a premature stop codon and amino acid deletion in the PirA protein. Methods CRAB strains obtained from patients admitted in a single medicine ward of the IRCCS...

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Antibiotic Resistance in Bacteria
Antibiotic Use and Resistance
Antibiotics Pharmacokinetics and Efficacy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39614286
DOI: 10.1186/s12941-024-00763-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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