Article

Structural Basis for Receptor Recognition by Lujo Virus

2018-05-24

Abstract excerpt

Lujo virus (LUJV) has emerged as a novel and highly fatal human pathogen. Despite its membership among the Arenaviridae , LUJV does not classify with the known Old and New World groups of that viral family. Likewise, LUJV was recently found to use neuropilin-2 (NRP2) as a cellular receptor instead of the canonical α-dystroglycan (α-DG) or transferrin receptor 1 (TfR1) utilized by Old World (OW) and New World (NW)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e404bd79-4be7-58f7-a989-4323dab2574e
DOI: 10.1101/329482

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Structural Basis for Receptor Recognition by Lujo VirusDOI 10.1101/329482Read

Structural basis for receptor recognition by Lujo virus.Semantic proximity Read

The structure of the Lujo virus spike complexSemantic proximity Read

Molecular Mechanism for LAMP1 Recognition by Lassa VirusSemantic proximity Read

Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural StudiesSemantic proximity Read

Lassa Virus Cell Entry Reveals New Aspects of Virus-Host Cell InteractionSemantic proximity Read

Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry.Semantic proximity Read

New World Clade B Arenaviruses Can Use Transferrin Receptor 1 (TfR1)-Dependent and -Independent Entry Pathways, and Glycoproteins from Human Pathogenic Strains Are Associated with the Use of TfR1Semantic proximity Read

Unusual Molecular Architecture of the Machupo Virus Attachment GlycoproteinSemantic proximity Read

Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenavirusesSemantic proximity Read

Viral receptors for flaviviruses: Not only gatekeepersSemantic proximity Read

Cells under siege: Viral glycoprotein interactions at the cell surfaceSemantic proximity Read

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B ArenavirusesSemantic proximity Read