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Article

Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies

27 Nov 2014

Abstract excerpt

Receptor recognition by viruses is the first and essential step of viral infections of host cells. It is an important determinant of viral host range and cross-species infection and a primary target for antiviral intervention. Coronaviruses recognize a variety of host receptors, infect many hosts, and are health threats to humans and animals. The receptor-binding S1 subunit of coronavirus spike proteins contains...

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PMID: 25428871
DOI: 10.1128/jvi.02615-14

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