Article

<i>O</i> -GlcNAcylation is essential for rapid <i>Pomc</i> expression and cell proliferation in corticotropic tumor cells

2021-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in many patients due to profound endocrine and neurologic dysfunction. To date, no clear genomic or epigenomic markers correlates with their onset or severity. Herein, we investigate the impact of the O -GlcNAc post-translational modification in their etiology. Found in over 5000 human proteins to date, O -Gl...

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Literature Corpus work: e3ea31b6-88d8-5f18-bf12-a7fc6389bc42
DOI: 10.1101/2021.08.13.455965

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