Article

Whole Genome Sequencing and single-cell transcriptomics identify<i>KMT2D</i>as a potential new driver for pituitary adenomas

2024-09-18

Abstract excerpt

The pituitary gland is a main component of the endocrine system and a master controller of hormone production and secretion. Unlike neoplastic formation in other organs, Pituitary Neuroendocrine Tumors (PitNETs) are frequent in the population (16%) and, for unknown reasons, almost exclusively benign. So far, few genes have been identified as drivers for PitNETs, such as GNAS in somatotroph tumors and USP8 in corti...

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Literature Corpus work: bb67695d-df47-5d00-ab7b-8f44d3628425
DOI: 10.1101/2024.09.17.24312241

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