Article

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

2020-08-17

Abstract excerpt

The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair and disease. Angiogenesis is regulated by intracellular endothelial signalling pathways, induced downstream of Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). A major challenge in understanding angiogenesis is interpreting how signalling events occur dynamically within endothelial cell pop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e3ddc22c-d1e9-5c18-bb23-4115694fd245
DOI: 10.1101/2020.08.17.254912

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesisDOI 10.1101/2020.08.17.254912Read

Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for DifferentiationSemantic proximity Read

Quantifying endothelial cell proliferation in the zebrafish embryoSemantic proximity Read

FRET imaging of Teen sensor captures ERK activation changes preceding morphological defects in a RASopathy zebrafish model and phenotypic rescue by MEK inhibitorSemantic proximity Read

Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2.Semantic proximity Read

A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification.Semantic proximity Read

Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesisSemantic proximity Read

Automated high-throughput live cell monitoring of endothelial cell migrationSemantic proximity Read

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish.Semantic proximity Read

Mouse flt-1 promoter directs endothelial-specific expression in the embyroid body model of embryogenesis.Semantic proximity Read

[Experimental angiogenesis : strategy for the functional study of the transcription factors of the Ets family during morphogenesis of the vascular tree].Semantic proximity Read

Assessment of the FRET-based Teen sensor to monitor ERK activation changes preceding morphological defects in a RASopathy zebrafish model and phenotypic rescue by MEK inhibitor.Semantic proximity Read

In vivo modulation of endothelial polarization by Apelin receptor signallingSemantic proximity Read