Article

Widespread 3D genome reorganization precedes programmed DNA rearrangement in <i>Oxytricha trifallax</i>

2025-01-02

Abstract excerpt

Genome organization recapitulates function, yet ciliates like Oxytricha trifallax possess highly-specialized germline genomes, which are largely transcriptionally silent. During post-zygotic development, Oxytricha ’s germline undergoes large-scale genome editing, rearranging precursor genome elements into a transcriptionally-active genome with thousands of gene-sized nanochromosomes. Transgenerationally-inherite...

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Literature Corpus work: e3b3999e-710b-51a7-a028-f6fed623584f
DOI: 10.1101/2024.12.31.630814

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