Article

SIGAR: Inferring features of genome architecture and DNA rearrangements by split read mapping

2020-05-07

Abstract excerpt

Ciliates are microbial eukaryotes with distinct somatic and germline genomes. Post-zygotic development involves extensive remodeling of the germline genome to form somatic chromosomes. Ciliates therefore offer a valuable model for studying the architecture and evolution of programmed genome rearrangements. Current studies usually focus on a few model species, where rearrangement features are annotated by aligning...

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Literature Corpus work: 31abbb8f-a6c8-5d86-bfa4-df0c9f24a88f
DOI: 10.1101/2020.05.05.079426

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