Article
The logic of containing tumors
2020-01-29
Abstract excerpt
Challenging the paradigm of the maximum tolerated dose, recent studies have shown that a strategy aiming for containment, not elimination, can control tumor burden more effectively in vitro , in mouse models, and in the clinic. These outcomes are consistent with the hypothesis that emergence of resistance to cancer therapy may be prevented or delayed by exploiting competitive ecological interactions between drug-...
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Identifiers and source
- Literature Corpus work
- e3afffe9-d444-5a5c-b595-53db25fa0f31
- DOI
- 10.1101/2020.01.22.915355