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The Depletion of the “Don’t-Eat-Me” Signal CD47 Increases Radiosensitivity through Phenotypical Attenuation of Cancer Stem Cell and EMT Properties in Oral Squamous Cell Carcinoma Cells

2019-07-04

Abstract excerpt

<h4>Background: </h4> Oral squamous cell carcinoma (OSCC), with poor prognosis and high mortality rates, is one of the most diagnosed head and neck cancers. Cancer stem cells (CSCs) - epithelial-to-mesenchymal transition (EMT) loop is increasingly implicated in the therapy-resistance, relapse, and metastasis of OSCC patients. Accumulating evidence indicate that aberrantly expressed CD47 is associated with cell-dea...

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Literature Corpus work
e385113f-6df1-5913-a920-c8c3d14238e4
DOI
10.20944/preprints201907.0079.v1
Open publication

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The Depletion of the &ldquo;Don&rsquo;t-Eat-Me&rdquo; Signal CD47 Increases Radiosensitivity through Phenotypical Attenuation of Cancer Stem Cell and EMT Properties in Oral Squamous Cell Carcinoma CellsDOI 10.20944/preprints201907.0079.v1
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