Article

SOX2 predicts local spreading and promotes a cancer stem cell-like phenotype in oral squamous cell carcinoma

2023-01-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Emerging evidence points toward the idea that oral squamous cell carcinoma (OSCC) invasiveness can be attributed to the existence of a small subpopulation of cancer stem cells (CSCs) in the bulk of the tumor. However, knowledge about the existence of CSCs in the OSCC close margins and their possible role in determining OSCC phenotypes is still far from being sati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c4e23802-fa88-548a-8b4e-dd9534c90a51
DOI: 10.21203/rs.3.rs-2385706/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SOX2 predicts local spreading and promotes a cancer stem cell-like phenotype in oral squamous cell carcinomaDOI 10.21203/rs.3.rs-2385706/v1Read

SOX2 promotes a cancer stem cell-like phenotype and local spreading in oral squamous cell carcinoma.Semantic proximity Read

Diversity of the Origin of Cancer Stem Cells in Oral Squamous Cell Carcinoma and Its Clinical ImplicationsSemantic proximity Read

Sox2 expression involvement in the oncogenicity and radiochemoresistance of oral cancer stem cellsSemantic proximity Read

Identification and characterization of CD133+CD44+ cancer stem cells from human laryngeal squamous cell carcinoma cell linesSemantic proximity Read

Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell CarcinomaSemantic proximity Read

High CD44 Immunoexpression Correlates with Poor Overall Survival: Assessing the Role of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma Patients from the High-Risk Population of PakistanSemantic proximity Read

Association of OCT 4, SOX 2, and NANOG expression with oral squamous cell carcinoma progressionSemantic proximity Read

Identification of Phenotypically Distinct Cancer Stem Cell Subpopulations in Oral Squamous Cell CarcinomaSemantic proximity Read

MSX2 represses tumor stem cell phenotypes within oral squamous cell carcinomas via SOX2 degradation.Semantic proximity Read

Targeting cancer stem cells in squamous cell carcinomaSemantic proximity Read

Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinomaSemantic proximity Read

Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinomaSemantic proximity Read