Article

MAP3K19 regulatory variation in populations with African ancestry is associated with severe COVID-19

2022-11-18

Abstract excerpt

<title>Abstract</title> <p>Ancestry impacts the likelihood of hospitalization due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). To identify ancestry-linked genetic risk variants associated with COVID-19 hospitalization, we performed an integrative analysis of two genome-wide association studies (GWASs) evaluating genetic variation among ancestrally diverse cohorts. We resolved four single nucleo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e34077e4-3b71-51eb-bdcf-00e8f35e21e7
DOI: 10.21203/rs.3.rs-2282081/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MAP3K19 regulatory variation in populations with African ancestry is associated with severe COVID-19DOI 10.21203/rs.3.rs-2282081/v1Read

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.Semantic proximity Read

Genome-wide association studies of COVID-19: Connecting the dotsSemantic proximity Read

Genetic risk factors associated with SARS-CoV-2 susceptibility in multiethnic populationsSemantic proximity Read

Genome-wide association study of hospitalized COVID-19 patients in the United Arab Emirates.Semantic proximity Read

AncestryDNA COVID-19 Host Genetic Study Identifies Three Novel LociSemantic proximity Read

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.Semantic proximity Read

A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of deathSemantic proximity Read

Detailed stratified GWAS analysis for severe COVID-19 in four European populationsSemantic proximity Read

Mapping the human genetic architecture of COVID-19 by worldwide meta-analysisSemantic proximity Read

GWAS and meta-analysis identifies multiple new genetic mechanisms underlying severe Covid-19Semantic proximity Read

Genetic determinants of severe COVID-19 in young Asian and Middle Eastern patientsSemantic proximity Read

Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19.Semantic proximity Read