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Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells

2023-10-09

Abstract excerpt

Immune checkpoint inhibitors (ICIs) have demonstrated efficacy and improved survival in a growing number of cancers. Despite their success, ICIs are associated with immune-related adverse events that can interfere with their use. Therefore, safer approaches are needed. CD6, expressed by T-lymphocytes and human NK cells, engages in cell-cell interactions by binding to its ligands CD166 (ALCAM) and CD318 (CDCP1). CD...

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Literature Corpus work
e2ebbe49-864a-5390-9b6b-6cc75d2aab82
DOI
10.21203/rs.3.rs-3405677/v1
Open publication

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Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer CellsDOI 10.21203/rs.3.rs-3405677/v1
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