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Article

Roles for the FCRL6 Immunoreceptor in Tumor Immunology

14 Oct 2020

Abstract excerpt

Members of the Fc receptor-like (FCRL1-6) gene family encode transmembrane glycoproteins that are preferentially expressed by B cells and generally repress responses via cytoplasmic tyrosine-based regulation. Given their distribution and function, there is a growing appreciation for their roles in lymphoproliferative disorders and as immunotherapeutic targets. In contrast to FCRL1-5, FCRL6 is distinctly expressed...

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PMID: 33162991
DOI: 10.3389/fimmu.2020.575175

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