Article

c-Myc promotes pulmonary fibrosis by driving myofibroblast activation and cellular senescence

2026-07-12

Abstract excerpt

<title>Abstract</title> <p> Background Idiopathic pulmonary fibrosis (IPF) is a devastating and progressive interstitial lung disease characterized by aberrant myofibroblast activation, cellular senescence, and excessive extracellular matrix (ECM) deposition. However, the precise molecular switches governing these pathogenic processes in lung fibroblasts remain incompletely understood. Although the transcriptio...

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Literature Corpus work: e2c75316-8e22-52b8-9010-157b7cd4f288
DOI: 10.21203/rs.3.rs-10232185/v1

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