Article

Penetrance of breast cancer genes from the eMERGE III Network

2021-04-26

Abstract excerpt

We studied the penetrance and clinical outcomes of seven breast cancer susceptibility genes ( BRCA1, BRCA2, TP53, CHEK2, ATM, PALB2 and PTEN ) in almost 25,000 participants unselected for personal or family history of breast cancer. We identified 420 participants with pathogenic or likely pathogenic variants, and 147 were women who did not previously know their genetic results. Out of these 147 women, 32 women wer...

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Literature Corpus work: e2c321ef-2766-5fb2-83d0-238d1a518e35
DOI: 10.1101/2021.04.24.21255936

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