Toward a better understanding of the experience of patients with moderate penetrance breast cancer gene pathogenic/likely pathogenic variants: A focus on ATM and CHEK2.

Abstract excerpt

This study explored the experiences of patients with pathogenic or likely pathogenic variants in the moderate penetrance breast cancer genes, ATM and CHEK2. There were 139 eligible female patients who received genetic counseling at the Massachusetts General Hospital Center for Cancer Risk Assessment (MGH CCRA) from 2014 to 2018. They were sent surveys assessing their understanding of the clinical significance of...

Topics

• Ataxia Telangiectasia Mutated Proteins
• Breast Neoplasms
• Checkpoint Kinase 2
• Female
• Genetic Counseling
• Genetic Predisposition to Disease
• Genetic Testing
• Humans
• Penetrance