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Article

Diversity and evolution of archaeal immune strategies.

Nucleic acids research - 24 Feb 2026

Martínez-Alvarez Laura, Peng Xu

Abstract excerpt

Archaeal antiviral defense systems remain poorly characterized despite recent advances in understanding prokaryotic immunity. Here, we analyze 7747 archaeal genomes, the largest and most diverse dataset to date, revealing a striking disparity in defense system prevalence and diversity compared to Bacteria. Nearly one-third of archaeal genomes have no detected systems beyond CRISPR-Cas and restriction-modification...

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Identifiers

PMID: 41830331
DOI: 10.1093/nar/gkag225
PMCID: PMC12988326

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PDC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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